Table 5.
Association of the CETP rs5882 V/V genotype with lipid levels
| All | I/I + I/V (n = 937) | V/V (n = 77) | P-value | r2 |
| HDL mean mg/dl (SD) | 50.3 (13.2) | 53.8 (17.0) | 0.03 | 0.007 |
| LDL mean mg/dl (SD) | 126.4 (38.3) | 128.9 (42.6) | 0.62 | 0.005 |
| Triglycerides mean mg/dl (SD) | 128.4 (58.1) | 138.5 (91.4) | 0.18 | 0.010 |
| Female | I/I + I/V (n = 464) | V/V (n = 39) | P-value | r2 |
| HDL mean mg/dl (SD) | 51.7 (12.9) | 56.9 (16.5) | 0.02 | 0.011 |
| LDL mean mg/dl (SD) | 129.2 (40.8) | 132.8 (44.5) | 0.94 | 0.001 |
| Triglycerides mean mg/dl (SD) | 138.7 (60.6) | 145.1 (86.2) | 0.56 | 0.007 |
| Male | I/I + I/V (n = 473) | V/V (n = 38) | P-value | r2 |
| HDL mean mg/dl (SD) | 48.8 (13.3) | 50.7 (17.3) | 0.46 | 0.009 |
| LDL mean mg/dl (SD) | 123.6 (35.6) | 124.9 (40.6) | 0.92 | 0.024 |
| Triglycerides mean mg/dl (SD) | 118.3 (40.8) | 131.9 (97.2) | 0.19 | 0.018 |
Age-adjusted P-values were determined by linear regression. Subjects with cardiovascular diseases were excluded due to lipid lowering therapy. r 2 = coefficient of determination, SD = standard deviation, significant values are shown bold