. 2016 Jul 21;16:232. doi: 10.1186/s12906-016-1217-7

Table 4.

Effects of AF and honey on the Liver and kidney structure

Changes/lesions in liver	A (Control) Mean ± SD	B (AF-treated) Mean ± SD	C (AF+Honey-treated) Mean ± SD	P values
1. Enlargement and palaness	-/6^b	2/6^a	-/6^b	*
slight	*	2	*
Moderate	*	*	*
Severe	*	*	*
2. Hydrolic degeneration/ or fatty changes	-/6^b	6/6^a	6/6^c
Slight	*	*	4	**
Moderate	*	2	2
Severe	*	4	*
3. Dysplastic hepatocytes	-/b^b	6/6^a	4/6^c	**
Slight	*	*	2
Moderate	*	3	2
Severe	*	3	*
4. Bile-duct proliferation	-/6^b	5/6^a	2/6^c	**
5. Periportal fibrosis	-/6^b	6/6^a	1/6^b	*
Slight	*	2	1
Moderate	*	2	*
Severe	*	2	*
6. Degeneration and necrosis in renal tubule epithelial cells	-/6^b	6/6^a	2/6^c	*
Slight	*	2	2
Moderate	*	4	*
Severe	*	*	*
7. Megalocytosis in renal tubule epithelial cells	-/6^b	2/6^a	-/6^b
Slight	*	2	*
Moderate	*	*	*
Severe	*	*	*

The values present the number of rats showing change/number of rats examined in each treatment group. Values with different letters (a, b and c) in same row are significantly different (P <0.01), according to the Chi-Square tests.

*P >0.05

**P <0.01