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. 2016 Jul 20;16:506. doi: 10.1186/s12885-016-2526-4

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Expression of EpCAM ^mRNA+ CTC and Treg/CD4+ in HCC recurrence vs no recurrence group. a, Based on 2^−ΔΔC _q algorithm transformation, the relative EpCAM mRNA expression of CTC in HCC patients with or without tumor recurrence after resection. EpCAM ^mRNA+ CTC showed significantly higher in recurrence patients (p = 0.001); b, The high ratio of Treg/CD4⁺ was observed d in recurrence group (p = 0.0197)