Table 2.

Combinations of variables used for DDF classification and grading grouped by different interpretations of the EACVI/ASE 2009 classification algorithm in studies in which the algorithm interpretation was specified (n = 47)

Classification and grading of DDF by a one-level classification tree (n = 13)S1–S13	Classification and grading of DDF by a two-level classification tree (n = 18)S14–S31	Classification of DDF only, no grading (n = 16)S32–S47
For the definition of DDF and grading:	For the definition of DDF:	For the definition of DDF:
E/A, E/E′, and DT (n = 4)S1,S2,S6,S12	E′ (n = 8)S14,S16,S17,S20,S26,S27,S29,S30	E/E′ (n = 6)S35,S40,S42,S45–S47
E/A and PV (n = 3)S3–S5	E′ and LA size (n = 6)S15,S18,S21,S23,S25,S31	LA size and E/E′ (n = 3)S36,S41,S43
E/A, E/E′, VSr, DT, and IVRT (n = 1)S10	E/E′ (n = 2)S22,S24	DT and IVRT (n = 1)S34
E/A, PV, E/E′, and DT (n = 1)S9	E′, LA size, and E/E′ (n = 1)S28	E′ (n = 1)S33
E/A, PV, DT, and IVRT (n = 1)S11	E′, E/A, and DT (n = 1)S19	E′, E/E′, and E/A (n = 1)S32
E/A, PV, DT, IVRT, and E′/A′ (n = 1)S7		LA size (n = 1)S39
E/A, VSr, and DT (n = 1)S13	For the subsequent grading of DDF:	LA size, E/E′, and E/A (n = 1)S44
E′, LA size, E/A, and E/E′ (n = 1)S8	E/A and DT (n = 5)S18,S22,S24,S25,S29	E/E′, E/A, and DT (n = 1)S38
	E/A, E/E′, and DT (n = 4)S21,S26,S27,S30	E′ and LA size (n = 1)S37
	DT (n = 2)S14,S28
	E/A (n = 2)S17,S20
	E/A, E/E′, DT, and IVRT (n = 1)S23
	E′, E/A, E/E′, and DT (n = 1)S19
	E′, LA size, E/A, and E/E′ (n = 1)S15
	Variables used not specified (n = 2)S16,S31

S1–S60 denotes references available in Supplementary material online.

DDF, diastolic dysfunction; E′, septal, lateral, average, or unspecified early myocardial tissue velocity; E, early transmitral flow velocity; A, late/atrial transmitral flow velocity; LA size, left atrial volume, diameter, or area; DT, deceleration time; IVRT, isovolumetric relaxation time; VSr, Valsalva reversal of E/A; PV, pulmonary venous flow indices.