Table 1.
Patient characteristics
| Controls | BAV | TAV |
P-value Controls vs. BAV |
P-value Controls vs. TAV |
P-value TAV vs. BAV |
P-value overall | |
|---|---|---|---|---|---|---|---|
| n | 65 | 50 | 50 | ||||
| Age (years) | 43 ± 14 (78, 19) | 49 ± 14 (80, 23) | 61 ± 14 (85, 26) | 0.017 | <0.001 | <0.001 | <0.001 |
| Female | 25 (38%) | 12 (24%) | 9 (18%) | 0.101 | 0.018 | 0.464 | 0.041 |
| Height (m) | 1.72 ± 0.08 (1.90, 1.52) | 1.77 ± 0.08 (1.96, 1.55) | 1.61 ± 0.19 (1.93, 1.27) | 0.002 | 0.017 | <0.001 | <0.001 |
| Weight (kg) | 84 ± 19 (136, 54) | 83 ± 13 (123, 59) | 86 ± 17 (140, 43) | – | – | – | 0.561 |
| Effective orifice area (cm2) | 2.6 ± 0.5 (1.8, 4.0) | 2.0 ± 0.7 (0.9, 3.5) | 2.5 ± 0.8 (0.9, 3.9) | <0.001 | 0.65 | 0.001 | <0.001 |
| Stenosis severity | |||||||
| Mild | 0 (0%) | 14 (28%) | 7 (14%) | <0.001 | 0.002 | 0.087 | <0.001 |
| Moderate | 0 (0%) | 3 (6%) | 0 (0%) | 0.046 | – | 0.08 | 0.03 |
| Severe | 0 (0%) | 0 (0%) | 0 (0%) | – | – | – | – |
| Regurgitation severity | |||||||
| Mild | 0 (0%) | 6 (12%) | 4 (8%) | 0.004 | 0.021 | 0.5 | 0.023 |
| Moderate | 0 (0%) | 4 (8%) | 7 (14%) | 0.021 | 0.002 | 0.34 | 0.011 |
| Severe | 0 (0%) | 1 (2%) | 1 (2%) | – | – | – | 0.317 |
All continuous data are presented as mean ± standard deviation (max, min) or number (%). P-value resulted from independent-sample t-test (Gaussian distribution) or Mann–Whitney (non-Gaussian distribution) comparing subjects groups.
BAV, bicuspid aortic valve; TAV, tricuspid aortic valve.