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. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Prog Biophys Mol Biol. 2015 Dec 30;120(1-3):18–27. doi: 10.1016/j.pbiomolbio.2015.12.014

Figure 1.

Figure 1

The degrees of freedom (d.o.f.) used to simulate the large and gradual conformational changes within the Kv7.1 channel during gating. A) 3 translational and 3 rotational degrees of freedom for the rigid body motion of the VSD (S3–S4 complex). B) 2 dihedral angles for the conformational changes of the S4–S5 linker. C) 6 dihedral angles for the bending of the S6 segment. D) 3 translational and 3 rotational d.o.f. for the rigid body motion of S6.