. Author manuscript; available in PMC: 2016 Jul 21.

Published in final edited form as: J Med Chem. 2015 Mar 30;58(7):3002–3024. doi: 10.1021/jm501440q

Table 6.

Growth inhibition studies were performed as described for Table 3. Cells were incubated in serial dilutions of 4da for 3 days before determining viable cell numbers relative to untreated cells.

Cell Line or Strain	Cell Type	Inhibition (IC₅₀, µM)
H460	lung cancer	15.9 ± 1.1
HeLa	uterine cervical cancer	10.8 ± 0.8
HEK-293	embryonic kidney	10.4 ± 1.3
JJN3	myeloma	15.7 ± 0.9
INA-6	myeloma	18.1 ± 0.8
IH-1	myeloma	20.6 ± 1.1
ANBL-6	myeloma	35.6 ± 2.6
KJON	myeloma	23.0 ± 2.6
U266	myeloma	46.0 ± 3.2
HO15.19 (myc−/−)	rat fibroblasts	20.6 ± 1.0
HO15.19-wt-Myc	rat fibroblasts	14.1 ± 1.2