Table 2.
Cognitive scores at baseline and follow-up (N = 60)
| Cognitive Domain | Baseline (Mean ± SD) |
Follow-Up (Mean ± SD) |
Change (Mean ± SD) (95% CI) |
p value† |
|---|---|---|---|---|
| Wechsler FSIQ | 104.6 (13.3) | 104.1 (12.1) | −0.43 (7.9) (−2.47 – 1.60) |
0.67 |
| Verbal Comprehension | 107.6 (12.7) | 108.5 (12.6) | 0.93 (6.9) (−0.85 – 2.71) |
0.30 |
| Perceptual Reasoning/Organization | 104.5 (12.5) | 106.0 (13.1) | 1.52 (9.9) (−1.04 – 4.07) |
0.24 |
| Working Memory | 102.0 (12.4) | 103.9 (12.8) | 1.87 (11.0) (−0.98 – 4.70) |
0.19 |
| Processing Speed | 95.1 (15.8) | 89.9 (11.4) | −5.23 (12.3) (−8.41 – −2.05) |
0.002 |
| Coding raw score | 45.0 (17.1) | 48.9 (15.2) | 3.87 (16.2) (−0.33 – 8.05) |
0.07 |
| Coding scaled score* | 8.8 (3.4) | 7.9 (2.9) | −0.83 (2.8) (−1.55 – 0.10) |
0.03 |
| Symbol Search raw score | 25.2 (7.3) | 27.4 (9.7) | 2.17 (10.4) (−0.52 – 4.85) |
0.11 |
| Symbol Search scaled score* | 9.4 (2.6) | 8.6 (2.3) | −0.82 (2.4) (−1.44 – 0.19) |
0.01 |
IQ, Intelligence Quotient; SD, standard deviation; CI, Confidence Interval of the Difference
*
For scaled scores, mean = 10, standard deviation = 3
†
Statistical significance of change in mean scores at follow-up from paired t-test analysis.