Table 3.

Association between cholesterol levels and cognitive impairment among 2,000 Chinese elderly

Variable	Crude OR (95% CI)	Basic model † (aOR, 95% CI)	Final model ‡ (aOR, 95% CI)
TC
Each1mmol/L increment in TC	0.78(0.71–0.86)**	0.75 (0.67–0.85)**	0.75 (0.66–0.85)**
Tertiles of TC
Low	1.00 reference	1.00 reference	1.00 reference
Middle	0.73(0.58–0.92)**	0.73 (0.56–0.97)*	0.74 (0.56–0.98)*
High	0.73(0.65–0.83)**	0.73 (0.63–0.84)**	0.73 (0.62–0.84)**
Triglycerides
Each1mmol/L increment	0.67 (0.56–0.80)**	0.80 (0.65–0.98)*	0.80 (0.65–1.00)*
Tertiles of TG
Low	1.00 reference	1.00 reference	1.00 reference
Middle	0.94 (0.75–1.18)	0.88 (0.67–1.15)	0.89 (0.67–1.17)
High	0.80 (0.71–0.90)**	0.86 (0.74–1.00)*	0.88 (0.76–1.03)
LDL-C
Each1mmol/L increment	0.80 (0.72–0.89)**	0.75 (0.65–0.87)**	0.75 (0.65–0.87)**
Tertiles of LDL-C
Low	1.00 reference	1.00 reference	1.00 reference
Middle	0.83 (0.64–1.08)	0.69 (0.51–0.94)*	0.70 (0.51–0.96)*
High	0.87 (0.76–0.99)*	0.81 (0.70–0.95)**	0.82 (0.70–0.96)*
HDL-C
Each1mmol/L increment	0.82 (0.63–1.07)	0.72 (0.52–0.99)*	0.73 (0.53–1.01)
Tertiles of HDL-C
Low	1.00 reference	1.00 reference	1.00 reference
Middle	0.89 (0.71–1.12)	0.91 (0.69–1.19)	0.91 (0.68–1.20)
High	0.90 (0.80–1.00)*	0.82 (0.71–0.94)**	0.81 (0.70–0.94)**

TC =Total cholesterol; TG=triglycerides, LDL-C =low density lipoprotein; HDL-C=high density lipoprotein; OR=odds ratio; aOR=adjusted odds ratio; CI=confidence interval.

^*p<0.05;

^**p<0.01.

^†Adjusted for potential confounders included age, gender, marital status, residence and education level.

^‡Adjusted for potential confounders including age, gender, marital status, residence, education level, and current cigarette smoking, current alcohol drinking, central obesity, sleep quality, anemia, hypertension, type 2 diabetes mellitus and CKD.