Table 4.

Association between cholesterol level and cognitive impairment and cholesterol in 2,000 Chinese elderly, by gender and age group

Variable	Gender†		Age group†
	Men (n=934)	Women (n=1066)	Young elderly (age ≤79, n=703)	Oldest old (age ≥80, n=1297)
TC
Each1mmol/L increment	0.74(0.60–0.93)**	0.76(0.65–0.88)**	0.77(0.55–1.10)	0.75(0.66–0.86)**
Tertiles of TC
Low	1.00 reference	1.00 reference	1.00 reference	1.00 reference
Middle	0.88(0.57–1.36)	0.65(0.45–0.95)**	0.66(0.31–1.41)	0.77(0.57–1.07)
High	0.71(0.55–0.94)*	0.71(0.59–0.86) **	0.78(0.53–1.16)	0.71(0.61–0.84)**
TG
Each1mmol/L increment	0.84(0.6–1.26)	0.79(0.61–1.02)	1.14(0.77–1.67)	0.72(0.55–0.92)*
Tertiles of LDL-C
Low	1.00 reference	1.00 reference	1.00 reference	1.00 reference
Middle	1.08(0.67–1.69)	0.82(0.57–1.19)	0.62(0.27–1.41)	0.92(0.68–1.24)
High	0.93(0.71–1.21)	0.85(0.70–1.03)	0.87(0.59–1.26)	0.87(0.74–1.03)
LDL-C
Each1mmol/L increment	0.69(0.53–0.91)**	0.77(0.65–0.92)**	0.66(0.44–0.99)*	0.76(0.65–0.89)**
Tertiles of LDL-C
Low	1.00 reference	1.00 reference	1.00 reference	1.00 reference
Middle	0.62(0.39–0.97)*	0.76(0.52–1.10)	0.78(0.38–1.62)	0.70(0.51–0.96)*
High	0.84(0.65–1.07)	0.77(0.64–0.93)**	0.72(0.49–1.08)	0.82(0.70–0.96)*
HDL-C
Each1mmol/L increment	0.84(0.47–1.48)	) 0.67(0.45–1.00)*	1.04(0.45–2.40	0.69(0.49–0.99)*
Tertiles of HDL-C
Low	1.00 reference	1.00 reference	1.00 reference	1.00 reference
Middle	0.68(0.43–1.07)	1.08(0.75–1.56)	0.85(0.41–1.80)	0.92(0.68–1.25)
High	0.82(0.64–1.05)	0.80(0.67–0.96)*	0.85(0.57–1.29)	0.81(0.70–0.95)**

TC =Total cholesterol; TG=triglycerides, LDL-C =low density lipoprotein; HDL-C=high density lipoprotein.

^*p<0.05;

^**p<0.01.

Data in the table are adjusted odds ratio (OR) and 95% confidence intervals (CI, in parentheses).

^†Adjusted for potential confounders including age, gender, marital status, residence education level, current cigarette smoking practices, current alcohol drinking habits, central obesity, sleep quality, anemia, hypertension, type 2 diabetes mellitus and CKD.