Table II.
Demographic and risk factor data by gender-specific CAC quartile, entire population: AGES-Reykjavik study.
| Variable | CAC Quartile
|
|||||
|---|---|---|---|---|---|---|
| All | 1 | 2 | 3 | 4 | p | |
| Men | n = 848 | n = 212 | n = 212 | n = 212 | n = 212 | |
| Age (years)* | 76.1 (5.4) | 74.8 (5.4) | 76.0 (5.1) | 76.8 (5.4) | 76.7 (5.7) | <0.001 |
| BMI (kg/m2)* | 26.7 (3.7) | 26.4 (3.7) | 26.2 (3.5) | 26.7 (3.4) | 27.3 (4.2) | 0.02 |
| Systolic BP (mmHg)* | 142.3 (20.5) | 141.8 (21.0) | 144.7 (22.3) | 142.5 (18.8) | 140.0 (19.6) | 0.15 |
| Diastolic BP (mmHg)* | 76.0 (9.3) | 77.1 (9.3) | 76.9 (9.6) | 75.3 (8.8) | 74.6 (9.2) | 0.02 |
| Total cholesterol (mmol/L)* | 5.2 (1.0) | 5.5 (0.9) | 5.3 (1.0) | 5.1 (1.1) | 5.1 (1.0) | <0.001 |
| LDL cholesterol (mmol/L)* | 3.3 (0.9) | 3.6 (0.7) | 3.4 (0.9) | 3.2 (1.0) | 3.1 (0.9) | <0.001 |
| Use of antilipemic medication (%) | 26.7 | 9.4 | 17.9 | 31.6 | 47.6 | <0.001 |
| Diabetes mellitus (%) | 14.9 | 11.8 | 15.6 | 15.6 | 16.5 | 0.53 |
| Smoking Status: | ||||||
| Current (%) | 17.6 | 17.0 | 20.8 | 18.4 | 14.2 | <0.001 |
| Former (%) | 56.4 | 46.7 | 52.8 | 57.6 | 68.4 | |
| Hypertension (%) | 65.9 | 59.4 | 72.6 | 65.1 | 66.5 | 0.04 |
| CHD (%) | 32.4 | 11.8 | 22.6 | 41.0 | 54.2 | <0.001 |
| Peripheral arterial disease (%)† | 7.5 | 4.2 | 5.2 | 8.5 | 12.3 | 0.01 |
| Women | n = 1 156 | n = 289 | n = 290 | n = 288 | n = 289 | |
| Age (years)* | 76.0 (5.7) | 73.6 (5.1) | 75.1 (5.5) | 77.0 (5.2) | 78.3 (5.7) | <0.001 |
| BMI (kg/m2)* | 27.1 (4.9) | 27.2 (4.3) | 27.3 (4.9) | 27.1 (5.4) | 26.9 (4.9) | 0.77 |
| Systolic BP (mmHg)* | 141.8 (21.4) | 137.8 (19.4) | 140.9 (20.7) | 142.2 (22.4) | 146.3 (22.2) | <0.001 |
| Diastolic BP (mmHg)* | 72.2 (9.1) | 73.0 (8.2) | 72.6 (8.9) | 71.6 (9.2) | 71.7 (10.2) | 0.23 |
| Total cholesterol (mmol/L)* | 6.1 (1.1) | 6.1 (1.0) | 6.2 (0.9) | 6.1 (1.2) | 5.9 (1.1) | 0.01 |
| LDL cholesterol (mmol/L)* | 3.8 (1.0) | 3.9 (0.9) | 3.9 (0.9) | 3.8 (1.1) | 3.7 (1.1) | 0.02 |
| Use of antilipemic medication (%) | 15.7 | 6.9 | 12.4 | 15.3 | 28.0 | <0.001 |
| Diabetes mellitus (%) | 9.5 | 6.2 | 6.9 | 11.1 | 13.8 | 0.005 |
| Smoking status: | ||||||
| Current (%) | 12.2 | 9.3 | 13.8 | 12.6 | 13.2 | 0.001 |
| Former (%) | 32.3 | 26.0 | 30.8 | 31.1 | 41.3 | |
| Hypertension (%) | 71.3 | 62.6 | 73.4 | 71.5 | 77.5 | 0.001 |
| CHD (%) | 14.7 | 5.9 | 7.9 | 16.0 | 29.1 | <0.001 |
| Peripheral arterial disease (%)† | 3.7 | 0.3 | 2.8 | 5.2 | 6.6 | 0.58 |
*
Mean (SD).
†
Intermittent claudication by self-report or history of peripheral arterial bypass surgery or angioplasty.
BMI indicates body mass index; BP, blood pressure; CAC, coronary artery calcium; CHD, coronary heart disease; LDL, low-density lipoprotein.