Table 2.

The minimal SR value and the corresponding slope. In each bracket, the first value is the minimal SR value in different category and the second values is the corresponding slope. N>5 and N>10 means that only the SAVs, which are observed at least five or ten times in the datasets, will be used for SR calculation

	$P_p^{r,k}$ (N>5)	$P_p^{r,k}$ (N>10)	$P_p^k$ (1kcal/mol, N>5)	$P_p^k$ (1kcal/mol, N>10)	$P_p^k$ (Optimal threshold, N>5)	$P_p^k$ (Optimal threshold, N>10)
SR (folding)	(1.66, 0.96)	(0.78, 1.04)	(2.79, 1.64)	(1.63, 1.85)	(2.1, 1.25)	(1.14, 1.37)
SR (binding)	(2.71, 0.84)	(0.13, 0.75)	(3.91, 1.45)	(0.86, 1.43)	(2.84, 0.98)	(0.24, 0.82)