Skip to main content
. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Mini Rev Med Chem. 2016;16(5):358–369. doi: 10.2174/1389557515666151001154002

Fig. (2). Inhibition of Ras maturation.

Fig. (2)

Newly-synthesized Ras polypeptides undergo complex, multi-step maturation pathways. Many of the enzymes shown have been considered as potential therapeutic targets. In addition to those detailed in this figure, both Rce1 and Icmt have also been investigated [see 5 for review].