TABLE 2.
Patient and Treatment Characteristics Independently Associated with Earlier Onset-to-Reperfusion Times
| Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|
| Patient Characteristic | Estimate | SE | p | Estimate | SE | p |
| Age, per 5-year increments | 1.92 | 2.73 | 0.483 | — | — | — |
| Female sex | −20.4 | 14.01 | 0.146 | −25.8 | 14.26 | 0.072 |
| NIHSS, per 5-point increments | 13.41 | 7.56 | 0.078 | 15.83 | 7.33 | 0.032 |
| Atrial fibrillation | 19.74 | 14.02 | 0.161 | — | — | — |
| Hypertension | 5.32 | 14.01 | 0.704 | — | — | — |
| Coronary artery disease/ myocardial disease |
−14.8 | 16.24 | 0.362 | — | — | — |
| Diabetes | 70.65 | 17.12 | 0.000 | 49.17 | 17.98 | 0.007 |
| Hyperlipidemia | −31.0 | 13.81 | 0.026 | −28.8 | 13.96 | 0.040 |
| Peripheral artery disease | 39.76 | 56.35 | 0.481 | — | — | — |
| Smoking | 6.37 | 18.93 | 0.737 | — | — | — |
| Previous stroke/TIA | −13.1 | 17.62 | 0.458 | — | — | — |
| mRS 1—5 | 12.46 | 16.09 | 0.440 | — | — | — |
| M1 vs. ICA | −7.75 | 19.41 | 0.690 | — | — | — |
| M2 vs. ICA | 17.13 | 27.75 | 0.540 | — | — | — |
| M3 vs. ICA | 78.00 | 61.09 | 0.213 | — | — | — |
| Receipt of IV t-PA | −23.2 | 14.27 | 0.106 | — | — | — |
| Baseline ASPECTS ≥ 6 | −25.2 | 22.38 | 0.261 | — | — | — |
NIHSS = National Institutes of Health Stroke Scale/Score; TIA = transient ischemic attack; mRS = modified Rankin Scale; ICA = internal carotid artery; IV = intravenous; tPA = tissue-type plasminogen activator; SE = standard error.