Table 1.
Subject demographic and neuropsychological data
| Non-carriers (n= 19) | PSEN1 Carriers (n=20) | p-value | |
|---|---|---|---|
| Gender | 16 females/ 3 males | 15 females/ 5 male | |
| Age | 34.45 (6.29) | 34.04 (5.87) | 0.83 |
| Range | 24–49 | 25–44 | |
| Education | 10.80 (3.28) | 10.77 (2.30) | 0.79 |
| Range | 5–16 | 6–16 | |
|
| |||
| CERAD Tests | |||
| MMSE/ 30 | 29.5 (1.0) | 29.6 (0.5) | 0.51 |
| Verbal Fluency | 19.65 (5.38) | 18.57 (4.51) | 0.31 |
| Naming/ 15 | 13.55 (1.50) | 13.86 (1.08) | 0.52 |
| Memory Words | |||
| Reading | 10 (0.00) | 10 (0.00) | |
| Total Correct/ 30 | 19.35 (3.49) | 20.40 (3.34) | 0.32 |
| Total Intrusions | 1.65 (2.3) | 0.86 (0.99) | 0.17 |
| Recall of Words | |||
| Total Correct/ 10 | 7.15 (1.49) | 6.86 (1.58) | 0.32 |
| Total Intrusions | 0.35 (0.67) | 0.22 (0.42) | 0.35 |
| Recognition of Words | |||
| Correct “yes” /10 | 9.55 (0.82) | 9.81 (0.39) | 0.12 |
| Correct “no” /10 | 9.95 (0.22) | 10 (0.00) | 0.31 |
| Constructional Praxis/ 11 | 9.75 (0.96) | 9.86 (1.03) | 0.84 |
| Recall of Drawings/ 11 | 9.15 (1.92) | 8.31 (2.16) | 0.13 |
Values denote mean (+/− Standard Deviation)