Table 5.
| a. Uni- and multivariable Cox proportional hazard analysis of predictors for overall PCa incidence | ||||||
|---|---|---|---|---|---|---|
| Univariate | Multivariate | |||||
| Hazard ratio | 95% CI | p-value | Hazard ratio | 95% CI | p-value | |
| Baseline Characteristics | ||||||
| Age, years | 1.05 | 1.03 – 1.07 | < 0.0001 | 1.04 | 1.02 – 1.06 | < 0.0001 |
| PSA, ng/ml | 1.13 | 1.12 – 1.14 | < 0.0001 | 1.13 | 1.12 – 1.14 | < 0.0001 |
| Family History | 1.58 | 1.21 – 2.07 | 0.001 | 1.63 | 1.24 – 2.14 | < 0.0001 |
| IPSS | 1.02 | 1.01–1.04 | 0.002 | 1.01 | 0.99 – 1.02 | 0.3 |
| b. Uni- and multivariable Cox proportional hazard analysis of predictors for aggressive* PCa incidence | ||||||
|---|---|---|---|---|---|---|
| Univariate | Multivariate | |||||
| Hazard ratio | 95% CI | p-value | Hazard ratio | 95% CI | p-value | |
| Baseline Characteristics | ||||||
| Age, years | 1.04 | 1.01 – 1.07 | 0.003 | 1.03 | 1.00 – 1.07 | 0.06 |
| PSA, ng/ml | 1.14 | 1.13 – 1.16 | < 0.0001 | 1.14 | 1.12 – 1.16 | < 0.0001 |
| Family History | 1.30 | 0.82 – 2.06 | 0.26 | 1.52 | 0.92 – 2.51 | 0.1 |
| IPSS | 1.00 | 0.97–1.03 | 0.9 | 0.98 | 0.95 –1.01 | 0.2 |
*
Aggressive PCa was defined as Gleason score ≥ 7