Table 4. Performance of the Framingham Steatosis Index using cut-points of predicted risk.
| FSI cut-points | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|
| FHS Cohort | ||||
| ≥9 vs <9 | 95 | 44 | 38 | 96 |
| ≥14 vs <14 | 90 | 58 | 44 | 94 |
| ≥20 vs < 20 | 83 | 67 | 48 | 91 |
| ≥23 vs < 23 | 79 | 71 | 50 | 90 |
| ≥26 vs < 26 | 77 | 75 | 53 | 90 |
| ≥28 vs < 28 | 75 | 78 | 55 | 89 |
| ≥32 vs <32 | 70 | 83 | 60 | 88 |
| NHANES III | ||||
| ≥9 vs <9 | 84 | 52 | 30 | 93 |
| ≥14 vs <14 | 76 | 66 | 35 | 92 |
| ≥20 vs < 20 | 66 | 76 | 40 | 90 |
| ≥23 vs < 23 | 62 | 80 | 42 | 90 |
| ≥26 vs < 26 | 58 | 81 | 43 | 89 |
| ≥28 vs < 28 | 55 | 84 | 45 | 89 |
| ≥32 vs <32 | 51 | 87 | 48 | 88 |
FSI, Framingham steatosis index; PPV, positive predictive value; NPV, negative predictive value; NHANES, National Health and Nutrition Survey