. Author manuscript; available in PMC: 2017 Aug 1.

Published in final edited form as: Osteoarthritis Cartilage. 2016 Apr 9;24(8):1350–1356. doi: 10.1016/j.joca.2016.04.001

Table 3.

Associations between the predictor variables and incident knee replacement from 0–30 and 60–84 months (combined)¹

		crude model		adjusted model[1]²		adjusted model[2]²		adjusted model[3]²
Sex	Predictor (KR/knee visits included in analysis)	odds ratio (95% CI)	P- value	odds ratio (95% CI)	P- value	odds ratio (95% CI)	P- value	odds ratio (95% CI)	P- value
Men	Knee extensor strength in Nm (50/658)	1.00 (0.99,1.01)	0.79	1.01 (1.00,1.02)	0.19	1.01 (1.00,1.02)	0.07	1.01 (1.00,1.02)	0.05^*
	Chair stand time in s. (73/882)	1.03(0.97,1.10)	0.285	1.01(0.93,1.09)	0.805	1.00(0.92,1.08)	0.926	1.00(0.92,1.09)	0.984
	PASE (75/926)	1.00(1.00,1.00)	0.52	1.00(1.00,1.00)	0.64	1.00(1.00,1.00)	0.48	1.00(1.00,1.00)	0.78
Women	Knee extensor strength in Nm (121/1,285)	0.98(0.97,0.99)	<.001^*	0.98(0.97,0.99)	<.001^*	0.99(0.98,1.00)	<.01^*	0.99(0.98,1.00)	0.27
	Chair stand time in s. (149/1,621)	1.05(1.01,1.09)	<.01^*	1.04(1.00,1.08)	0.03^*	1.02(0.98,1.06)	0.27	1.03(0.98,1.07)	0.20
	PASE (174/1,787)	1.00(1.00,1.00)	0.91	1.00(1.00,1.00)	0.16	1.00(1.00,1.00)	0.11	1.00(1.00,1.00)	0.26

The number of knees with incident knee replacement in men was less than the required number by rule of thumb (10 outcome events per predictor variable). The number of knee visits in the table corresponds to the number of knees evaluated at 30 or 84 months. KR=Knee replacement; PASE= Physical Activity Scale for the Elderly

Adjusted for: [1] Age, BMI, race, site, education, occupation, knee injury, surgery; [2] Age, BMI, race, site, education, occupation, knee injury, surgery, WOMAC knee pain; [3] Age, BMI, race, site, education, occupation, knee injury, surgery, WOMAC knee pain, KL grade.

Significant (p < 0.05) associations are indicated by *.