Table 5.

Selected proteins with highest difference in abundance in BALF of cases with IPS compared to infectious lung injury.

Uniprot Accession Number	Protein Name	Mean variance weighted fold change IPS: mastermix	Mean Variance weighted Fold change Infection: marstermix	FDR (Comparing fold change in IPS vs infectious lung injury)	Fold Change IPS: Infection
Proteins that are high in IPS compared to infectious lung injury (ten proteins with highest differential expression)
tr|F6SYF8|F6SYF8_HUMAN	Dickkopf-related protein 3	8.87	2.71	8.98E-03	3.27
sp|P24158|PRTN3_HUMAN	Myeloblastin	1.09	0.34	5.27E-03	3.25
sp|Q9BTY2|FUCO2 HUMAN	Plasma alpha-L-fucosidase	4.10	1.53	8.05E-03	2.69
sp|O95497|VNN1_HUMAN	Pantetheinase	4.97	1.87	1.07E-02	2.66
sp|P14151|LYAM1_HUMAN	L-selectin	2.33	0.89	1.17E-03	2.63
sp|P13598|ICAM2_HUMAN	Intercellular adhesion molecule 2	2.63	1.25	3.64E-02	2.10
sp|P22352|GPX3_HUMAN	Glutathione peroxidase 3	0.96	0.47	8.41E-06	2.06
sp|P48637|GSHB_HUMAN	Glutathione synthetase	2.15	1.10	1.59E-03	1.96
sp|Q6UX71|PXDC2 HUMAN	Plexin domain-containing protein 2	4.16	2.21	2.66E-02	1.89
sp|P01033|TIMP1_HUMAN	Metalloproteinase inhibitor 1	0.69	0.37	2.49E-04	1.85
Proteins that are high in infectious lung injury compared to IPS (ten proteins with highest differential expression)
tr|H0Y7A7|H0Y7A7_HUMAN	Calmodulin (Fragment)	0.51	0.90	1.42E-03	0.57
sp|P07108-5|ACBP_HUMAN	Isoform 5 of Acyl-CoA-binding protein	1.02	1.78	2.10E-02	0.57
sp|P61626|LYSC_HUMAN	Lysozyme C	0.27	0.47	2.57E-05	0.57
sp|P01011|AACT_HUMAN	Alpha-1-antichymotrypsin	0.68	1.22	3.31E-06	0.56
sp|Q8WUM4|PDC6I_HUMAN	Programmed cell death 6-interacting protein	1.12	2.01	2.49E-04	0.56
sp|Q16651|PRSS8_HUMAN	Prostasin	1.80	3.23	8.98E-03	0.56
tr|X6R8F3|X6R8F3_HUMAN	Neutrophil gelatinase-associated lipocalin	0.30	0.54	1.30E-03	0.56
sp|P15311|EZRI_HUMAN	Ezrin	0.83	1.49	2.56E-08	0.55
sp|P05109|S10A8_HUMAN	Protein S100-A8 SV=1	0.15	0.28	6.90E-04	0.54
sp|P08118|MSMB_HUMAN	Beta-microseminoprotein	0.81	1.87	3.10E-03	0.43