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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Nanomedicine. 2016 Apr 9;12(6):1535–1542. doi: 10.1016/j.nano.2016.03.009

Figure 2. Experimental protocol schematic.

Figure 2

For all experiments after the pilot MRI study, neuroinflammatory insult was administered at time (t)=0, IV ferumoxytol or saline (control) was administered at t=24 h, and MRI was performed at t=48 h. Immediately after MRI brains were extracted for immunohistochemistry (IHC) analysis, immunofluorescent histochemistry (IFHC) analysis, and electron microscopy (EM) analysis.