Table 3.
Maximum Grade of Toxicities
| During RT, No. (%) |
After RT, No. (%) |
|||||
|---|---|---|---|---|---|---|
| Toxicity Grade | Placebo Arm (n=42) | Treatment Arm (n=42) | P Valuea | Placebo Arm (n=29) | Treatment Arm (n=25)^ | P Valuea |
| Tenesmus | .23a | .64a | ||||
| 0 | 30 (71) | 27 (64) | 21 (72) | 18 (78) | ||
| 1 | 9 (21) | 6 (14) | 7 (24) | 5 (22) | ||
| 2 | 3 (7) | 7 (17) | 1 (3) | 0 (0) | ||
| 3 | 0 (0) | 2 (5) | ||||
| Abdominal pain | .30a | .02a | ||||
| 0 | 26 (62) | 22 (52) | 24 (83) | 17 (68) | ||
| 1 | 12 (29) | 14 (33) | 2 (7) | 8 (32) | ||
| 2 | 4 (10) | 3 (7) | 3 (10) | 0 (0) | ||
| 3 | 0 (0) | 3 (7) | ||||
| Constipation | .70a | .63a | ||||
| 0 | 27 (64) | 26 (62) | 22 (76) | 19 (76) | ||
| 1 | 13 (31) | 12 (29) | 6 (21) | 6 (24) | ||
| 2 | 2 (5) | 4 (10) | 1 (3) | 0 (0) | ||
| Diarrhea | .44a | .48a | ||||
| 0 | 11 (26) | 10 (24) | 14 (48) | 11 (44) | ||
| 1 | 14 (33) | 13 (31) | 10 (35) | 12 (48) | ||
| 2 | 13 (31) | 9 (21) | 3 (10) | 2 (8) | ||
| 3 | 4 (10) | 9 (21) | 2 (7) | 0 (0) | ||
| 4 | 0 (0) | 1 (2) | ||||
| Rectal bleeding | .38 | .15a | ||||
| 0 | 22 (52) | 26 (62) | 27 (93) | 20 (80) | ||
| 1 | 20 (48) | 16 (38) | 2 (7) | 5 (20) | ||
Abbreviation: RT, radiation treatment.
a
χ2 test.
^
Data incomplete on two patients