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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: J Immunol. 2016 Jun 17;197(3):899–909. doi: 10.4049/jimmunol.1600502

Figure 3. Increased macrophage influx in Mmp10−/− lungs.

Figure 3

Mmp10−/− and wildtype mice (n = 6–8/genotype/time point) were infected with P. aeruginosa, and BAL and lung tissue were collected 4 and 48 h later. In BAL samples, total cell (A) and neutrophil (B) counts did not differ between genotypes. (C) Macrophage numbers in BAL did not differ at 4 h post-infection, but at 48 h, about 3-fold more macrophages were detected in Mmp10−/− BAL compared to wildtype. *p = 0.0045 by unpaired t-test. (D) Sections of wildtype (WT) and Mmp10−/− lungs collected at 48 h post-infection were stained for macrophages with Mac-2 antibody.