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. Author manuscript; available in PMC: 2016 Jul 21.
Published in final edited form as: Cosmetics. 2016 Feb 19;3(1):6. doi: 10.3390/cosmetics3010006

Figure 2. Eucerin Smoothing lotion enhances GSH QD penetration through ex vivo mouse skin in the petri-dish protocol.

Figure 2

Figure 2

(a) Significant increase in the GSH QD presence was observed in the Eucerin smoothing lotion group at depths of 5 and 10 μm from the stratum corneum compared to water. All other vehicles exhibited QD penetration trends similar to or lower than the water treated group. Vaseline intensive care lotion exhibited negligible penetration; Mean ± SEM (N=4, n=3). (b) Three-dimensional reconstruction of the z stacks (0–40 μm) obtained by using CLSM shows that QDs do not penetrate skin by a uniform Fickian diffusion process. QDs appear to penetrate into the viable epidermis through high fluency entry points in the stratum corneum. *p<0.05 vs. water.