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. Author manuscript; available in PMC: 2016 Jul 21.
Published in final edited form as: Acta Ophthalmol. 2013 Jun 7;91(7):e537–e545. doi: 10.1111/aos.12146

Table 3.

Differentially regulated genes in the A2E/430 nm-S group.

Gene symbol Gene name Fold change
p-value adjusted*
A2E/430 nm-S A2E/430 nm-L
Immune response
 CEBPG CCAAT/enhancer binding protein (C/EBP), gamma   4.8   5.5 1.1E-02
 SQSTM1 Sequestosome 1   2.7   4.2 6.5E-03
 XBP1 X-box binding protein 1   2.2   2.4 5.3E-03
 GPI Glucose phosphate isomerase   0.5   0.5 5.7E-03
Anti-apoptotic
 ASNS Asparagine synthetase   4.0   3.5 9.9E-03
 NUAK2 NUAK family, SNF1-like kinase, 2   0.5   0.4 1.1E-02
Pro-apoptotic
 TRIB3 Tribbles homolog 3 (Drosophila) 10.9   7.4 5.5E-03
 SQSTM1 Sequestosome 1   2.7   4.2 6.5E-03
 RRAGC Ras-related GTP binding C   2.0   2.7 7.0E-03
Response to stress
 TRIB3 Tribbles homolog 3 (Drosophila) 10.9   7.4 5.5E-03
 SQSTM1 Sequestosome 1   2.7   4.2 6.5E-03
Positive regulation of proliferation
 HES1 Hairy and enhancer of split 1, (Drosophila)   0.3   0.2 1.3E-02
 EDN1 Endothelin 1   0.2   0.2 6.4E-03
Negative regulation of proliferation
 CDC6 Cell division cycle 6 homolog (S. cerevisiae)   2.7   2.3 5.5E-03
 DAB2 Disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)   2.1   1.8 1.1E-02
Cell cycle
 E2F7 E2F transcription factor 7   7.8 12.6 5.3E-03
 ASNS Asparagine synthetase   4.0   3.5 9.9E-03
 CDC6 Cell division cycle 6 homolog (S. cerevisiae)   2.7   2.3 5.5E-03
 RASSF1 Ras association (RalGDS/AF-6) domain family member 1   2.4   2.8 2.9E-03
 FBXO5 F-box protein 5   2.0   2.0 1.3E-02
 KANK1 KN motif and ankyrin repeat domains 1   0.5   0.6 6.5E-03
Autophagy
 WIPI1 WD repeat domain, phosphoinositide interacting 1   3.4   3.2 6.6E-03
Visual perseption
 DHRS3 Dehydrogenase/reductase (SDR family) member 3   0.4   0.3 9.6E-03
*

Adjusted p-value to false discovery rate according to the methods of (Benjamini & Hochberg 1995).