Table 3.
Differentially regulated genes in the A2E/430 nm-S group.
| Gene symbol | Gene name | Fold change
|
p-value adjusted* | |
|---|---|---|---|---|
| A2E/430 nm-S | A2E/430 nm-L | |||
| Immune response | ||||
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 4.8 | 5.5 | 1.1E-02 |
| SQSTM1 | Sequestosome 1 | 2.7 | 4.2 | 6.5E-03 |
| XBP1 | X-box binding protein 1 | 2.2 | 2.4 | 5.3E-03 |
| GPI | Glucose phosphate isomerase | 0.5 | 0.5 | 5.7E-03 |
| Anti-apoptotic | ||||
| ASNS | Asparagine synthetase | 4.0 | 3.5 | 9.9E-03 |
| NUAK2 | NUAK family, SNF1-like kinase, 2 | 0.5 | 0.4 | 1.1E-02 |
| Pro-apoptotic | ||||
| TRIB3 | Tribbles homolog 3 (Drosophila) | 10.9 | 7.4 | 5.5E-03 |
| SQSTM1 | Sequestosome 1 | 2.7 | 4.2 | 6.5E-03 |
| RRAGC | Ras-related GTP binding C | 2.0 | 2.7 | 7.0E-03 |
| Response to stress | ||||
| TRIB3 | Tribbles homolog 3 (Drosophila) | 10.9 | 7.4 | 5.5E-03 |
| SQSTM1 | Sequestosome 1 | 2.7 | 4.2 | 6.5E-03 |
| Positive regulation of proliferation | ||||
| HES1 | Hairy and enhancer of split 1, (Drosophila) | 0.3 | 0.2 | 1.3E-02 |
| EDN1 | Endothelin 1 | 0.2 | 0.2 | 6.4E-03 |
| Negative regulation of proliferation | ||||
| CDC6 | Cell division cycle 6 homolog (S. cerevisiae) | 2.7 | 2.3 | 5.5E-03 |
| DAB2 | Disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 2.1 | 1.8 | 1.1E-02 |
| Cell cycle | ||||
| E2F7 | E2F transcription factor 7 | 7.8 | 12.6 | 5.3E-03 |
| ASNS | Asparagine synthetase | 4.0 | 3.5 | 9.9E-03 |
| CDC6 | Cell division cycle 6 homolog (S. cerevisiae) | 2.7 | 2.3 | 5.5E-03 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 2.4 | 2.8 | 2.9E-03 |
| FBXO5 | F-box protein 5 | 2.0 | 2.0 | 1.3E-02 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.5 | 0.6 | 6.5E-03 |
| Autophagy | ||||
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | 3.4 | 3.2 | 6.6E-03 |
| Visual perseption | ||||
| DHRS3 | Dehydrogenase/reductase (SDR family) member 3 | 0.4 | 0.3 | 9.6E-03 |
Adjusted p-value to false discovery rate according to the methods of (Benjamini & Hochberg 1995).