Table III.
Genes of interest that were upregulated in eosinophils of the esophagus compared to the bone marrow in CC10Il13Tg/Pirb−/−mice but not in CC10Il13Tg/Pirb+/+mice
| Gene symbol | Fold change [Esophagus/Bone marrow] | |
|---|---|---|
| Surface molecules | Il5ra | 5.73 |
| Il12rb2 | 4.24 | |
| Notch2 | 3.69 | |
| Notch1 | 2.58 | |
| Bmpr2 | 2.52 | |
| Ifnar1 | 2.28 | |
| Cd300a | 2.61 | |
| Cell adhesion and migration molecules | Itgax | 6.04 |
| Itgb3 | 4.67 | |
| Itgal | 3.75 | |
| Vasp | 3.21 | |
| Ezr | 2.84 | |
| Acta1 | 2.75 | |
| Cd24a | 2.07 | |
| Enzymes | Capn2 | 5.66 |
| Mmp9 | 3.49 | |
| Adam19 | 2.73 | |
| Secreted factors | Il6 | 18.9 |
| Tnf | 5.72 | |
| Cxcl10 | 4.43 | |
| Tgfbi | 4.42 | |
| Ccl8 | 3.84 | |
| Areg | 2.18 | |
| Intracellular signaling molecules | Jun | 3.72 |
| Stat6 | 3.44 | |
| Nfkb2 | 2.90 | |
| Tnik | 2.71 | |
| Rela | 2.69 | |
| Fosl1 | 2.35 | |
| Jak2 | 2.25 | |
| Nfkbib | 2.24 | |
| Irak2 | 2.03 | |
| MicroRNA | Mir1957 | 9.22 |
| Mir142 | 8.29 | |
| Cell cycle molecules | Gadd45b | 5.63 |
| S100a6 | 2.09 | |
| Survival molecules | Bcl10 | 2.20 |