Fig. 2.

(A) Binary cell fate decisions made during early mouse development from the totipotent blastomeres to the extraembryonic tissues and the three germ layers at the end of gastrulation. (B) Schematic representation of the early mouse development from zygote (E0) to gastrulation (E6.5). Sagital views are shown, except the last one that shows a tranversal section across the primitive streak from the E6.5 embryo. (C) Schematic representation of Wnt/β-catenin signalling domains in E5.5 and E6.5 embryos, these include the VE, posterior epiblast, the primitive streak, mesoderm and definitive endoderm.