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Superposition of 1D 19F NMR spectra of (A) RT146tfmF, (B) RT146tfmF-V108I, and (C) RT146tfmF-K103N, in the absence (black) and presence of NVP (pink) or EFV (green). The 19F spectra in the presence of each NNRTI at 1:1 and 1:5 molar ratios are shown in light and dark colors, respectively.
