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Shown is the structure of hemagglutinin in H3N2 (accession number 4O5N). The five epitope regions (Gupta et al., 2006) are color coded: epitope A is red (19 amino acids), B is yellow (21 aa), C is orange (27 aa), D is blue (41 aa), and E is green (22 aa). Note epitope B was dominant in 2013/2014 and 2014/2015.
