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Bilateral L4 spinal nerve ligation produced mechanical allodynia in mice. SNL mice (n = 12) had significantly increased paw withdrawal frequencies in response to a .38 g von Frey hair for both hind paws six days after surgery compared with the sham group (n = 12). The results represent the mean ± SEM; **p < 0.01 compared with the sham group. SNL: spinal nerve ligation.
