Table 1.

Summary of whole-cell intracellular studies on the effects of DA (≥20 µM) bath application and AMPA/KAR-mediated EPSC modulation.

Region	Species	DA dose	eEPSC	mEPSC	sEPSC	Locus	References
PFC	Rat	20 µM	Increase	N/A	N/A	Post	Gonzalez-Islas and Hablitz45
	Rat	100 µM	Inhibit	N/A	N/A	N/A	Law-Tho et al.35
	Rat	100 µM	Inhibit	N/A	N/A	N/A	Otani et al.36
	Rat	100 µM	N/A	↑ Hz	N/A	N/A	Marek and Aghajanian53
	Ferret	10 mM local	Inhibit	N/A	N/A	Pre	Gao et al.51
NAc	Rat	50 µM	Inhibit	N/A	N/A	Pre	Zhang et al.39
	Rat	30 µM 30 µM	Inhibit Inhibit	N/A N/A	N/A N/A	Pre	Harvey and Lacey37 Harvey and Lacey41
	Rat	100 µM	Inhibit	N/A	N.A	Pre	Pennartz et al.44
	Rat	75 µM	Inhibit	↓ Hz	N/A	Pre	Nicola et al.40
Prelimbic Cortex	Rat	100 µM	N/A	No effect	↑ Hz	Pre	Wang et al., 2002
VTA	Rat	30 µM	Inhibit	↓ Hz	N/A	Pre	Koga and Momiyama, 2000
NTS	Rat	100 µM	Inhibit	N/A	↓ Hz	Pre	Kline et al. 2002
LEC	Rat	50 µM	Inhibit	N/A	N/A	Pre	Caruana and Chapman43
PBN	Rat	50 µM	Inhibit	↓ Hz	N/A	Pre	Chen et al.42
ACC	Mice	50 µM	Present	Present	Present	Present	Present

AMPA: α-amino-3-hydroxy-5-methyl-4isoxazolepropionic acid; KAR: kainite receptors; EPSCs: excitatory postsynaptic currents; DA: Dopamine; eEPSCs: evoked excitatory postsynaptic currents; mEPSCs: miniature excitatory postsynaptic currents; sEPSCs: spontaneous excitatory postsynaptic currents; PFC: prefrontal cortex; NAc: nucleus accumbens; VTA: ventral tegmental area; LEC: lateral entorhinal cortex; PBN: parabrachial nucleus; ACC: anterior cingulate cortex; N/A: authors did not perform the experiments; local, pressure application of DA at the local neuron.