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Eif4ebp2-deficient mice exhibit increased β-cell mass. A and D: Assessment of β-cell mass at 3 and 12 months of age in wild-type (WT; white bars) and Eif4ebp2−/− (black bars) mice. B and E: Proliferative index in sections stained for Ki67 and insulin. C and F: TUNEL assay in insulin-stained sections (apoptotic rate). Data are shown as mean ± SEM (n = 5 mice per group). *P < 0.05.
