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. 2016 Mar 29;12:1744806916633704. doi: 10.1177/1744806916633704

Figure 6.

Figure 6.

Effect of continuous-Gap 27 administration on SGC activation in TG after IANX. Photomicrographs of GFAP-IR and Cx43-IR cells encircled with FG-labeled TG neurons in naive rats (a), and GFAP-IR cells encircling FG-labeled TG neurons innervating the whisker pad skin on day 8 following sham operation (b) or IANX (c) with continuous administration of vehicle or Gap 27. Arrows denote FG-labeled TG neurons. Scale bars: 50 µm. Mean percentages (d) and size-frequency histograms illustrating distribution (e) of FG-labeled TG neurons encircled with GFAP-IR cells on day 8 after sham operation or IANX with continuous administration of vehicle or Gap 27. *p < 0.05, **p < 0.01 (n = 4 in each group; one-way analysis of ANOVA followed by Tukey’s multiple-comparison tests).