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. 2016 May 16;12:1744806916647376. doi: 10.1177/1744806916647376

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — Effects of intrathecal administration of Lenti-Cdh1-GFP on the expression of surface GluR1 subunit, erythropoietin-producing human hepatocellular receptor A4 (EphA4) and EphrinA1 in the ipsilateral dorsal horn of SNI rats. (a) Interactions between GluR1, Cdh1, EphA4, EphrinA1 and APC2 in the ipsilateral spinal cord were determined by co-immunoprecipitation analysis. (b) Western blotting analysis of changes in GluR1, EphA4 and EphrinA1 in the ipsilateral spinal cord at 14 days after intrathecal injection of recombinant lentivirus or vehicle in SNI model rats (n = 3 for GluR1 in each group; n = 4 for EphA4 and EphrinA1 in each group). *P < 0.05 versus sham; ^#P < 0.05 versus SNI + vehicle; ^&P < 0.05 versus SNI + Lenti-GFP; one-way ANOVA followed by Fisher’s LSD post hoc test. IP: immunoprecipitation; GluR1-Mem: GluR1 in the plasma membrane fraction.