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. 2016 Jul 21;11(7):e0158963. doi: 10.1371/journal.pone.0158963

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© 2016 Khan et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 6 — MEAD up-regulate pro-apoptotic proteins (p53, Bax) and down-regulates the anti-apoptotic protein (Bcl-2) in MCF7 cells. MCF7 cells were treated with 15 and 20 mg/ml MEAD and Bcl-2 inhibitor ABT-737 (10 μM) concentrations for 24 h and staining is performed for p53, Bax and Bcl-2. The representative graphs are out of three independent flow cytometric analyses.