Table 3. Hemodynamic and laboratory variables of the prewarming and control group during off-pump coronary artery bypass surgery.
| Group | Baseline | 1 H | 2 H | 3 H | End of surgery | |
|---|---|---|---|---|---|---|
| HR (beats/min) | P | 65 ± 8 | 58 ± 8 | 64 ± 13 | 64 ± 12 | 79 ± 13 |
| C | 68 ± 8 | 56 ± 9 | 58 ± 9 | 56 ± 11 | 79 ± 14 | |
| MBP (mmHg) | P | 103 ± 19 | 72 ± 10 | 71 ± 8 | 74 ± 9 | 74 ± 9 |
| C | 103 ± 19 | 72 ± 9 | 74 ± 7 | 78 ± 11 | 72 ± 7 | |
| MPAP (mmHg) | P | N/A | 13 ± 3 | 16 ± 2 | 16 ± 3 | 16 ± 4 |
| C | N/A | 13 ± 4 | 16 ± 4 | 15 ± 4 | 15 ± 5 | |
| CI (L/min/m2) | P | N/A | 2.1 ± 0.4 | 2.2 ± 0.5 | 2.2 ± 0.5 | 2.3 ± 0.4 |
| C | N/A | 2.2 ± 0.8 | 2.0 ± 0.3 | 2.1 ± 0.4 | 2.2 ± 0.4 | |
| SVV (%) | P | 10 ± 5 | 10 ± 4 | 10 ± 3 | 7 ± 3 | 10 ± 3 |
| C | 7 ± 3 | 10 ± 3 | 9 ± 4 | 7 ± 2 | 12 ± 4 | |
| Lactate (mmol/L) | P | 0.9 ± 0.4 | 0.9 ± 0.4 | 0.9 ± 0.3 | 0.8 ± 0.2 | 0.9 ± 0.3 |
| C | 0.9 ± 0.3 | 1.0 ± 0.4 | 1.0 ± 0.4 | 0.9 ± 0.4 | 1.0 ± 0.3 | |
| pH | P | 7.43 ± 0.03 | 7.44 ± 0.03 | 7.42 ± 0.04 | 7.42 ± 0.04 | 7.41 ± 0.04 |
| C | 7.43 ± 0.03 | 7.43 ± 0.05 | 7.42 ± 0.05 | 7.42 ± 0.06 | 7.40 ±0.05 | |
| Base deficit (mmol/L) | P | -1.8 ± 2.3 | -1.5 ± 2.1 | -0.9 ± 2.4 | -0.9 ± 2.4 | -0.5 ±2.0 |
| C | -2.0 ± 3.1 | -1.3 ± 3.4 | -1.1 ±3.2 | -0.7 ± 3.3 | 0.1 ± 3.0 | |
| Hematocrit (%) | P | 38 ± 4 | 32 ± 4 | 32 ± 4 | 31 ± 4 | 30 ± 2 |
| C | 38 ± 4 | 31 ± 4 | 31 ± 4 | 31 ± 4 | 31 ± 3 | |
| PaO2 (mmHg) | P | 80 ± 14 | 144 ± 50 | 168 ± 51 | 181 ± 41 | 137 ± 43 |
| C | 93 ± 36 | 165 ± 52 | 186 ± 40 | 192 ± 32 | 135 ± 33 | |
| SvO2 (%)* | P | N/A | 73 ± 5 | 72 ± 4 | 74 ± 5 | 75 ± 5 |
| C | N/A | 70 ± 6 | 70 ± 6 | 71 ± 6 | 70 ± 6 |
Values are means ± SD. Interaction between time and group was significant for HR (p = 0.012); and insignificant for MBP (p = 0.705), MPAP (p = 0.979), CI (p = 0.402), SVV (p = 0.069), lactate (p = 0.727), pH (p = 0.770), base deficit (p = 0.394), hematocrit (p = 0.716), PaO2 (p = 0.362), and SvO2 (p = 0.589).
* p < 0.05 between the groups.
1H, 1 h after induction of general anesthesia; 2H, 2 h after induction of general anesthesia; 3H, 3 h after induction of general anesthesia; HR, heart rate; P, prewarming group; C, control group; MBP, mean blood pressure; MPAP, mean pulmonary artery pressure; N/A, not assessed; CI, cardiac index; SVV, stroke volume variation; PaO2, arterial partial pressure of oxygen; SvO2, mixed venous oxygen saturation.
CI values are from FloTrac™/EV1000™ at the pre-induction period and from the pulmonary artery catheter/Vigilance™ II after induction of anesthesia.