Figure 12.

Reduction in ZnO NP-induced mitochondrial superoxide generation by differently charged (−35, −10, and +9 mV) CeO₂ NPs.

Notes: Mitochondrial superoxide generation in Jurkat cells was evaluated at 24 hours following concurrent exposure to ZnO (0.2 mM; −9 mV) and variously charged CeO₂ NPs (1 mM) using flow cytometry and MitoSOX™ Red staining. Results were analyzed using ANOVA, and statistical significance (P<0.05) was observed between all CeO₂ plus ZnO NP treatment groups and ZnO NP only treated samples, n=3.

Abbreviations: NP, nanoparticle; ANOVA, analysis of variance; NT, not treated.