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. 2016 Jul 15;9:29–45. doi: 10.2147/NSA.S99747

Figure 5.

Figure 5

Effects of NP charge on particle uptake.

Notes: Jurkat cells were treated with 0.15 mM ZnO NPs for 8 hours, separated from extracellular NP via positive immunomagnetic selection, and intracellular Zn ion concentration from equivalent number of cells was determined using ICP-MS. (A) Data from three independent experiments are presented with error bars depicting standard error and asterisks denoting statistical significance (P<0.05). Inset (B) depicts the percentage of zinc ions recovered using this assay from a sham sample of +44 mV ZnO NPs devoid of cells.

Abbreviations: NP, nanoparticle; ICP-MS, inductively coupled plasma mass spectrometry.