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. 2016 May 12;12:1744806916646785. doi: 10.1177/1744806916646785

Figure 4.

Figure 4.

(a and b) Intraperitoneal injection of ulinastatin (10,000, 50,000, or 100,000 U/kg) for seven days before L5-VRT increases the ipsilateral hindpaw withdrawal threshold and hindpaw withdrawal latency; however, no significant difference was obtained between the ulinastatin 10,000U/kg group and the L5-VRT group or between the ulinastatin100,000 U/kg group and the ulinastatin 50,000 U/kg group. *P < 0.05, **P < 0.01 versus the L5-VRT group. (c and d) Intraperitoneal injection of ulinastatin (50,000 U/kg) for seven days prevents the downregulation of CN induced by L5-VRT in the ipsilateral DRG (**P < 0.01 versus the sham group, ##P < 0.01 versus the L5-VRT group). L5-VRT: lumbar 5 ventral root transection; CN: calcineurin.