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. 2016 May 12;12:1744806916646785. doi: 10.1177/1744806916646785

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 5. — L5-VRT induces a significant decrease in the IL-10 protein level in the L4-L5 DRG on days 7, 10, and 14. (a) IL-10 upregulation was induced in the ipsilateral DRG after intrathecal injection of exogenous CN (10 U/day) for seven days. (b) IL-10 was also upregulated after intraperitoneal injection of ulinastatin (50,000 U/kg) for seven days. **P < 0.01 versus the sham group. ^#P < 0.05, ^##P < 0.01 versus the L5-VRT group. The IL-10 levels were determined with an ELISA. L5-VRT: lumbar 5 ventral root transection; CN: calcineurin.