Table 1. Fertility after ENU treatment.
| Genotype x dose1 | |||||
|---|---|---|---|---|---|
| Generation | Msh6+/+ x 90 | Msh6-/+ x 90 | Msh6-/- x 90 | Msh6-/- x 75 | |
| G01 | # males injected | 17 | 31 | 8 | 4 |
| # recovering fertility2 | 8 | 14 | 0 | 0 | |
| total # of progeny | 142 | 198 | 0 | 0 | |
| G02 | # males injected | 18 | 30 | ||
| # recovering fertility | 11 | 22 | |||
| total # of progeny | 101 | 140 | |||
| G03 | # males injected | 21 | 22 | ||
| # recovering fertility | 16 | 17 | |||
| total # of progeny | 118 | 248 | |||
| G04 | # males injected | 15 | |||
| # recovering fertility | 9 | ||||
| total # of progeny | 117 | ||||
1Dose is indicated as mg of ENU injected per Kg bodyweight x 3 injections.
2Fertility is measured by presence at least of one litter within 10 weeks after the last injection.