Table 2. Variant analysis for individual mice.
Genotype and Generation | variant for each individual | average | ratio1 | ratio H/W2 | ||
---|---|---|---|---|---|---|
wild-type G01 | 86 | 60 | 72 | 73 | 1.0 | |
wild-type G02 | 103 | 73 | 54 | 77 | 1.1 | |
wild-type G03 | 110 | 118 | 53 | 94 | 1.3 | |
Msh6+/- G01 | 70 | 77 | 49 | 65 | 1.0 | 0.9 |
Msh6+/-G02 | 135 | 106 | 57 | 99 | 1.5 | 1.3 |
Msh6+/- G03 | 108 | 56 | 124 | 96 | 1.5 | 1.0 |
1Ratio: the increase of variant present compared to the first ENU injection (G01)
2Ratio H/W: the increase of variant present in Msh6+/- compared to the same wild-type generation.