Table 3. Variant analysis for pooled mice.
Genotype and Generation | variants | ratio1 | ratio H/W2 |
---|---|---|---|
wild-type G01 | 186 | 1.00 | |
wild-type G02 | 259 | 1.39 | |
wild-type G03 | 295 | 1.59 | |
Msh6+/- G01 | 256 | 1.00 | 1.38 |
Msh6+/-G02 | 313 | 1.22 | 1.21 |
Msh6+/- G03 | 325 | 1.27 | 1.10 |
Msh6+/- G04 | 311 | 1.21 |
1Ratio: the increase of variant present compared to the first ENU injection (G01)
2Ratio H/W: the increase of variant present in Msh6+/- compared to the same wild-type generation.