Table 5. Characteristics of the simplified FINDRISC (MADRISC) questionnaire using different cut-off values for undiagnosed diabetes mellitus.
| GOLD STANDARD | MADRISC Cut-off | Sensitivity (%) (95%CI) | Specificity (%) (95%CI) | PPV (%) (95%CI) | NPV (%) (95%CI) | LR+(95%CI) | LR-(95%CI) |
|---|---|---|---|---|---|---|---|
| OGTT and/or HbA1c (N: 1,426 participants) | |||||||
| ≥8 | 99.1 (94.0–99.9) | 19.6 (17.5–21.9) | 8.9 (7.4–10.7) | 99.6 (97.5–99.9) | 1.23 (1.19–1.27) | 0.05 (0.01–0.34) | |
| ≥11 | 96.2 (89.9–98.8) | 24.8 (22.5–27.2) | 9.2 (7.6–11.1) | 98.8 (96.7–99.6) | 1.28 (1.22–1.34) | 0.15 (0.06–0.40) | |
| ≥13 | 84.8 (76.1–90.8) | 54.6 (51.9–57.3) | 12.9 (10.6–15.7) | 97.8 (96.4–98.7) | 1.87 (1.69–2.06) | 0.28 (0.18–0.44) | |
| ≥19 | 82.9 (74.0–89.3) | 55.7 (53.0–58.4) | 13.0 (10.6–15.8) | 97.6 (96.2–98.5) | 1.87 (1.68–2.08) | 0.31 (0.20–0.47) | |
| ≥20 | 69.5 (59.7–77.9) | 67.7 (65.1–70.2) | 14.6 (11.7–18.1) | 96.5 (95.1–97.6) | 2.15 (1.85–2.50) | 0.45 (0.34–0.60) | |
| ≥21 | 51.4 (41.5–61.2) | 81.8 (79.5–83.8) | 18.3 (14.2–23.3) | 95.5 (94.1–96.6) | 2.82 (2.27–3.51) | 0.59 (0.49–0.72) | |
| ≥24 | 51.4 (41.5–61.2) | 82.3 (80.1–84.3) | 18.8 (14.5–23.9) | 95.5 (94.1–96.6) | 2.90 (2.33–3.61) | 0.59 (0.48–0.72) | |
| ≥28 | 31.5 (27.3–35.9) | 92.6 (83.7–87.5) | 20.4 (15.7–26.0) | 95.5 (94.1–96.6) | 3.22 (2.56–4.06) | 0.60 (0.49–0.72) | |
| ≥32 | 24.8 (17.1–34.3) | 96.1 (94.8–97.0) | 33.3 (23.3–45.0) | 94.1 (92.7–95.3) | 6.29 (4.11–9.64) | 0.78 (0.70–0.87) | |
| ≥33 | 18.1 (11.5–27.1) | 97.2 (96.1–98.0) | 33.9 (22.2–47.9) | 93.7 (92.3–94.9) | 6.46 (3.86–10.83) | 0.84 (0.77–0.92) | |
| ≥41 | 12.4 (07.0–20.6) | 98.4 (97.5–99.0) | 38.2 (22.7–56.4) | 93.4 (91.9–94.6) | 7.79 (4.02–15.11) | 0.89 (0.83–0.96) | |