Table 2. Dependencies between predictive values and prevalence.
Prevalence | Very high Test Efficiency | Moderate Test Efficiency | ||
---|---|---|---|---|
Sensitivity and Specificity = 0.95, PLR = 19 | Sensitivity and Specificity = 0.7, PLR = 2.3 | |||
PPV | NPV | PPV | NPV | |
90% | 99.4% | 67.9% | 95.5% | 21% |
50% | 95.0% | 95.0% | 70% | 70% |
10% | 67.9% | 99.4% | 21% | 95% |
1% | 16.1% | > 99.9% | 2.3% | 99.6% |
0.1% | 1.9% | 100% | 0.2% | > 99.9% |
0.01% | < 0.2% | 100% | < 0.1% | 100% |
based on Mühlhauser and Höldke 1999; Bender, 2001; Grimes and Schulz, 2005