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. 2016 Jul 21;11(7):e0158850. doi: 10.1371/journal.pone.0158850

Table 2. Dependencies between predictive values and prevalence.

Prevalence Very high Test Efficiency Moderate Test Efficiency
Sensitivity and Specificity = 0.95, PLR = 19 Sensitivity and Specificity = 0.7, PLR = 2.3
PPV NPV PPV NPV
90% 99.4% 67.9% 95.5% 21%
50% 95.0% 95.0% 70% 70%
10% 67.9% 99.4% 21% 95%
1% 16.1% > 99.9% 2.3% 99.6%
0.1% 1.9% 100% 0.2% > 99.9%
0.01% < 0.2% 100% < 0.1% 100%

based on Mühlhauser and Höldke 1999; Bender, 2001; Grimes and Schulz, 2005