Table 1. Demographic, clinical, and social characteristics of patients receiving concurrent TB/HIV treatment in selected THAT’SIT clinics, South Africa, 2008–2010 (N = 1,252).
BMI = body mass index; TB = tuberculosis; IRZE = isoniazid, rifampin, pyrazinamide, ethambutol; DOT = directly observed therapy; WHO = World Health Organization; HIV = human immunodeficiency virus; ARV = antiretroviral; D4T/3TC/EFV = stavudine, lamivudine, efavirenz; D4T/3TC/NVP = stavudine, lamivudine, nevirapine.
| Characteristic | Total n (%†) |
|---|---|
| Age at concurrent treatment start, years | |
| <30 | 245 (19.6) |
| 30–39 | 568 (45.4) |
| 40–49 | 304 (24.3) |
| ≥50 | 135 (10.8) |
| Sex (n = 1247) | |
| Female | 698 (56.0) |
| Male | 549 (44.0) |
| Employment status (n = 1097) | |
| Employed | 232 (21.2) |
| Unemployed | 865 (78.9) |
| BMI at start of concurrent treatment (kg/m2) (n = 915) | |
| Underweight (<18.5) | 391 (42.7) |
| Normal (18.5–24.9) | 433 (47.3) |
| Overweight/Obese (≥25) | 91 (10.0) |
| Mental disorder (n = 985) | |
| No | 922 (93.6) |
| Yes | 63 (6.4) |
| Substance use (n = 782) | |
| No | 582 (74.4) |
| Yes | 200 (25.6) |
| TB patient category (n = 1247) | |
| New | 928 (74.4) |
| Retreatment | 319 (25.6) |
| TB site of disease | |
| Pulmonary | 1092 (87.2) |
| Extrapulmonary | 160 (12.8) |
| DOT for TB treatment | |
| DOT full treatment course | 1186 (94.7) |
| DOT intensive phase only | 26 (2.1) |
| DOT continuation phase only | 39 (3.1) |
| No DOT | 1 (0.1) |
| WHO clinical HIV stage | |
| Stage 1 | 72 (7.3) |
| Stage 2 | 100 (10.1) |
| Stage 3 | 530 (53.6) |
| Stages 4 | 287 (29.0) |
| ARV regimen (n = 1146) | |
| 1a (D4T/3TC/EFV) | 1072 (93.5) |
| 1b (D4T/3TC/NVP) | 74 (6.5) |
| CD4 at concurrent treatment start, (units) (n = 1011) | |
| ≤200 | 789 (78.0) |
| >200 | 222 (22.0) |
| Disclosed HIV status‡ (n = 1046) | |
| Yes | 1006 (96.2) |
| No | 40 (3.8) |
| Number of toxicities during the first 2 months of concurrent treatment | |
| None | 710 (56.7) |
| 1 | 274 (21.9) |
| ≥2 | 268 (21.4) |
†Percentages reflect the proportion among participants with a recorded value for each given variable (missing were excluded from percent), so totals may not add to 1252.
‡Variable indicates whether or not the patient reported disclosing his or her HIV status to a friend or family member.