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. 2016 Jul 21;11(7):e0157391. doi: 10.1371/journal.pone.0157391

Table 1. Binding affinities for TV1.C and 1086.C gp120 using various gp120 ligands.

Measurements were performed using SPR as described in Methods. For each ligand the target epitope is indicated in brackets.

mAb (epitope) KD (nM)
TV1.C gp120 1086.C gp120
CD4-Fc 148 26.6
b12 (CD4BS) DNB 88.1
VRC01 (CD4BS) DNB 93.5
2G12 (Mannose) 75 DNB
1B7A6 (V3) 3.5 30.5
10B6A8 (V3) 3.06 37.5
PG09 (V2-V3) 23.8 DNB
PG16 (V2-V3) DNB DNB
CH01 (V2-V3) DNB DNB
CH58 (V1V2) DNB 22.8
CH59 (V1V2) DNB 33.1

DNB = Did not bind