Table 1. Binding affinities for TV1.C and 1086.C gp120 using various gp120 ligands.
mAb (epitope) | KD (nM) | |
---|---|---|
TV1.C gp120 | 1086.C gp120 | |
CD4-Fc | 148 | 26.6 |
b12 (CD4BS) | DNB | 88.1 |
VRC01 (CD4BS) | DNB | 93.5 |
2G12 (Mannose) | 75 | DNB |
1B7A6 (V3) | 3.5 | 30.5 |
10B6A8 (V3) | 3.06 | 37.5 |
PG09 (V2-V3) | 23.8 | DNB |
PG16 (V2-V3) | DNB | DNB |
CH01 (V2-V3) | DNB | DNB |
CH58 (V1V2) | DNB | 22.8 |
CH59 (V1V2) | DNB | 33.1 |
DNB = Did not bind