Table 2. Unknown genes and genes without any interactions in STRING in predicted T. reesei secretion network.

Column ‘Gene’ contains the T. reesei gene ID. ‘In STRING’ tells if the gene has interactions in STRING. Columns ‘Btw’ and ‘Deg’ denote the betweenness and degree network statistics of the corresponding gene. Columns ‘Class’ and ‘Putative secretion pathway component’ are author assigned classifications. ‘Taxon specificity’ gives the largest taxonomic group the gene was found in.

Gene	STRING	Btw	Deg	Class	Protein family or Molecular function	Putative secretion pathway component	Taxon specificity
104448	NO	4075.6	66	Unknown		Protein folding	Pezizomycotina
111569	NO	217.4	43	Unknown		COPII	Pezizomycotina
112222	NO	1.0	2	Unknown	Tetratricopeptide-like helical	?	Pezizomycotina
46764	NO	0.4	7	Unknown		Protein glycosylation	Sordariomycetes
120000	YES	0.2	11	Unknown	Homeodoman superfamily	Protein folding	Trichoderma
105729	YES	0.0	11	Unknown		GPI-biosynthesis	Trichoderma
122293	NO	0.0	9	Unknown		Protein folding	Pezizomycotina
4791	NO	0.0	7	Unknown		COPII	Pezizomycotina
62041	NO	0.0	5	Unknown		Protein folding	Pezizomycotina
110342	YES	0.0	3	Unknown		Protein glycosylation	Pezizomycotina
104336	NO	0.0	2	Unknown	SnoaL-like domain	COPII	Trichoderma
110791	NO	0.0	2	Unknown		Protein glycosylation	Trichoderma
112490	NO	0.0	1	Unknown		?	Pezizomycotina
47424	YES	0.0	6	Unknown		GPI-biosynthesis	Sordariomycetes
65060	NO	0.0	17	Secretion	Golgi mannosyltransferase complex subunit	Golgi processing	Pezizomycotina
81211/ANP1	NO	0.0	2	Secretion	Golgi mannosyltransferase complex subunit	Golgi processing	Fungi
78463	NO	0.0	1	Regulatory functions	TPR repeat protein		Pezizomycotina
5275	NO	0.0	1	Chromatin modification			Fungi
27219	NO	0.0	2	Cell growth, wall, motility	Alpha-galactosidase		Trichoderma
65137	NO	0.0	2	Cell growth, wall, motility	Endo-1,3-beta-glucanase		Pezizomycotina