Author |
Year |
N |
AF Type |
Induction protocol |
Definition of inducibility |
Follow-up |
Results |
Haissaguerre et al. |
2004 |
70 |
AF with episode ≥ 1 hour |
Decremental burst pacing (5 sec) |
AF ≥ 1 min |
7±3 months |
87% of non-inducible patients vs. 62% of inducible patients (P=0.03) were AF-free |
Oral et al. |
2004 |
100 |
Paroxysmal AF |
Rapid atrial pacing (≥ 15 sec @ shortest cycle length with 1:1 atrial capture) |
AF > 1 min |
6 months |
85% of non-inducible patients after PVI vs. 67% of inducible patients after PVI vs. 86% patients who received further ablation after PVI when inducible were AF-free |
Essebag et al. |
2005 |
102 |
Paroxysmal and persistent AF |
Burst pacing (5 sec @ 200 ms) ± isoproterenol |
AF or left atrial tachycardia > 10 sec |
1 year |
72% of non-inducible patients vs. 53% of inducible patients (P=0.04) were AF-free |
Jais et al. |
2006 |
74 |
Paroxysmal AF |
Decremental burst pacing (10 sec) |
AF ≥ 10 min |
18±4 months |
91% of non-inducible patients were AF-free. |
Richter et al. |
2006 |
234 |
Paroxysmal (n=165) and persistent (n=69) AF |
Decremental burst pacing |
AF > 1 min |
6 months |
Non-inducibility had 46.7% sensitivity and 75% specificity for AF recurrence |
Chang et al. |
2007 |
88 |
Paroxysmal AF |
Decremental burst pacing (5-10 sec) |
AF or atrial flutter > 1 min |
12±6 months |
81% of non-inducible patients after PVI vs 84% of non-inducible patients after PVI plus additional ablation vs 45% of paitnets inducible after PVI plus additional ablation were AF-free |
Crawford et al. |
2010 |
112 |
Paroxysmal AF |
Decremental burst pacing (5-10 sec)Isoproterenol (up to 20 µg/min) |
AF up to 15 mins after infusion |
12±5 months |
84% of patients non-inducible with isoproterenol (33% sens, 97% spec), vs 76% of patients non-inducible by pacing (44% sens, 72% spec) were AF free |
|
|
|
|
Decremental burst pacing (10 sec) |
AF ≥ 1 min |
|
|
Satomi et al. |
2008 |
60 |
Paroxysmal AF |
Decremental burst pacing (10 sec) |
AF > 10 mins |
16±8 months |
58% of non-inducible patients vs 59% of inducible patients were AF free |
Leong-Sit et al. |
2013 |
144 |
Paroxysmal (n=78) and persistent (n=66) AF |
Decremental burst pacing (15 beats) |
AF or atrial tachycardia/flutter ≥ 2 mins |
1 year |
51% of non-inducible patients vs 51% of inducible patients were AF free |