Table 5.
Compound | CDb | IC50c | CId |
---|---|---|---|
1 | 19.8 | >40 | >2.4 |
2 | 2.2 | 17.8 | 8.1 |
3 | 2.4 | >40 | >16.8 |
8 | 1.8 | 35.0 | 19.4 |
11 | 6.6 | >40 | >7.1 |
l-sulforaphanee | 0.51 | 20.9 | 40.8 |
Data are represented as CD or IC50 values (µM, toward Hepa 1c1c7 cell line) and were calculated using nonlinear regression analysis with measurements performed in duplicate and representative of two independent readings in which the values generally agreed within 10%
The concentration required to double quinone reductase activity
The concentration that inhibits 50% cell growth
The chemopreventive index (IC50/CD)
Positive control