Study 1, Effects of gastric electrical stimulation (GES; 10 min) current (0.5, 1, or 2 mA) and frequency (8, 15, 30, or 60 Hz) at site 1 (Fig. 1) on emesis and esophageal contractions (n = 9/group). (A) Number of emetic episodes. (B) Cumulative proportion of animals showing the latency to the first emetic episode. (C) Number of esophageal contractions. Red dots = scatter plot of raw data; bars = mean ± SEM. * p < 0.05, LSD-test.